This will decrease in 48-72 hours, depending on the area and the amount of filler required to dissolve, however, it will take up to two weeks for the entire fill to completely dissolve and settle naturally. Most dermal fillers settle down or show their full results after 2 to 3 weeks, although there are a few exceptions. It takes time for the filler to break down, integrate with the tissue in the surrounding area, and begin to moisturize the skin. Most hyaluronic acid fillers used on the lips, jaw and cheeks, including Juvederm and Restylane, are metabolized after 6 months to a year.
Hyaluronic acid fillers, such as Juvederm, can be dissolved with the hyaluronidase enzyme, which starts working almost immediately.