To dissolve lip fillers, you'll need hyaluronidase (Hyalase) injections near the filler. When injected, it begins to break down the filler, accelerating the dissolution process that would take place over time. Hyaluronidase is a soluble protein enzyme that is normally used to break down hyaluronic acid found in dermal fillers. The solution works by breaking the bonds that hold HA molecules together and encourages the body to reabsorb those molecules in a natural process that it knows how to do on its own.
It achieves this by increasing tissue permeability, splitting the molecular bonds that hold hyaluronic acid together and promoting the natural cellular processes responsible for its diffusion. In cosmetic medicine, hyaluronidase is used to dissolve dermal fillers that have been improperly, excessively, or unevenly placed. It is also used in emergency situations where dermal filler has been inadvertently injected into an artery, causing occlusion of the blood supply. It is injected in the vicinity of the dermal filler that needs to be dissolved.
The action of hyaluronidase is very rapid and begins to act immediately on dermal fillers. Fillers are permanently dissolved and metabolized. Keep in mind that hyaluronidase does not work in permanent or semi-permanent dermal fillers.